Compstatin binds to C3 and C3b, preventing the match dysregulation caused by genetic mutations or by auto-antibodies. activating factors and regulating factors should be distinguished. Genetic mutations causing abnormalities either in activating or in regulating factors have been explained. The analysis of the match mediated MPGN requires a total study of all these different match … Continue reading Compstatin binds to C3 and C3b, preventing the match dysregulation caused by genetic mutations or by auto-antibodies